A new study offers a deeper understanding of the relationship between common oral bacteria and life-threatening diseases.

Researchers at the Karolinska Institute in Sweden have identified the most common bacteria in severe oral infections. The team now hopes the study will provide a deeper understanding of the relationship between oral bacteria and other diseases.

Previous research has shown a clear link between oral health and common life-threatening diseases such as cancer, cardiovascular disease, diabetes and Alzheimer’s disease. However, several longitudinal studies have been conducted to identify bacteria found in infected areas of the mouth and maxillofacial region.

Now, researchers at Karolinska Institutet have analyzed samples collected between 2010 and 2020 at Karolinska University Hospital in Sweden from case histories of patients with severe oral infections and compiled a list of the most common bacteria.

“Here, for the first time, we report the microbial composition of bacterial infections from samples collected over ten years in Stockholm County. The results show that many bacterial infections are associated with chronic systemic diseases,” says Professor Margrethe Saalberg-Schen from the University of Stockholm. Department of Dentistry, Karolinska Institute. Some of them have increased over the last decade in Stockholm.”

A study published in the journal Microbiology Spectrum found that the most common bacterial species among the samples were Streptococcus spp, Prevotella spp and Staphylococcus spp.

Professor Salberg Chen explains: “Our results provide new insights into the diversity and prevalence of harmful microbes in oral infections. This discovery is not only important for dentistry, but also helps us understand the role of dental infections in patients with comorbidities. Specifically, bacteria infect the oral cavity. and cause damage to it. It is very likely that they can damage tissues in other parts of the body as the infection spreads.”

The same research team had previously shown that the presence of oral bacteria in the pancreas reflects the severity of pancreatic tumors.

The study was conducted using 1014 patient samples, 469 women and 545 men. A mass spectrometry technique called MALDI-TOF can quickly identify individual live bacteria in samples, but this technique is rarely used in dentistry.

“Our study was a single-center epidemiological study, and to ensure the validity of the results, we need to do more, larger studies. Now we hope that dentists will collaborate more with clinical microbiology laboratories to better understand bacteria,” says Volkan. Ozenci from the Department of Laboratory Medicine at the Karolinska Institute that cause dental infections to improve the diagnosis and therapeutic treatment of oral infections.

Source: Medical Express