"Cancer test 4 in 1" Let women’s suffering end!

Scientists say a new test that can detect cervical cancer years before it appears could revolutionize screening for four types of cancer.

Experts believe the test, which can also detect DNA markers for other cancers, could be used to predict breast, uterine, cervical and ovarian cancers over several years – all from the same tampon. It could save thousands of women from burdensome cancer treatments and painful biopsies by identifying those most at risk before cancer develops.

It also marks the end of mammography, which is traditionally used to screen women over 50.

The new test looks at DNA methylation, an extra layer on top of DNA that tells cells their specific function.

By studying this with Pap smears, scientists have found that it is possible to track changes in cells before they become cancerous.

Current screening tests women for human papillomavirus (HPV), the virus responsible for 99% of cervical cancers.

Samples from women who test positive are examined under a microscope for cellular changes that can become cancerous.

The researchers studied 1,254 cervical screening samples from women with low to high risk cell changes, HPV-positive women with no cervical cell changes, and samples from women without any cervical cell changes who developed changes. four years.

And for women who don’t have cell changes but do have HPV, 55 percent of them will have cell changes within the next four years.

The test also performed better than currently available methods for identifying people with advanced cellular changes who need treatment, according to the findings, published in the journal Genome Medicine.

Scientists believe that by studying DNA methylation more closely, they can detect cancer and possibly predict a person’s risk of developing cancer in the future.

They also believe that cells taken during a Pap smear could signal future breast, ovarian, and uterine cancers, which they describe as a “surrogate effect.”

Dr. Chiara Herzog, from the University of Innsbruck in Austria, said other tests work by capturing cells produced by cancer, meaning the cancer must be present. But by studying a person’s DNA methylation, which can change with factors like age, pollution, and weight, a person’s likelihood of developing cancer can be predicted. The idea is that we can use one cervical cancer to predict four cancers.”

Professor Martin Widschwinter of the Department of Women’s Cancer at University College London has been working on the study for two decades.

He said: Vaccination against the virus that causes cervical cancer is now widely used and results in changes in the amount and types of virus circulating in society. In turn, our approaches to cervical screening must be adapted so that programs can continue to deliver value. Importantly, our other work has shown how testing the same sample of the cervix can also provide information about a woman’s risk of three other major cancers—breast, ovarian, and uterine. Establishing new comprehensive risk-predictive screening programs based on current and efficient cervical biopsy collection offers real potential for future cancer prevention.”

Source: Daily Mail

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