Groundbreaking Study Links Skin Microbiome to Wrinkles and Aging – What This Means for Anti-Aging Research

Skin Microbiome and Aging

In a groundbreaking new study, researchers have linked the skin microbiome to signs of aging such as wrinkles and overall skin health. This opens new horizons for understanding the effects of aging on the skin and perhaps alleviating them.

What is the Skin Microbiome?

The skin microbiome, a complex ecosystem of microorganisms that live on our skin, has long been a subject of interest to scientists and researchers.

The Study

This recent study revealed a possible link between the type of microorganisms present on the face and how we age, including the appearance of wrinkles such as so-called “crow’s feet”.

Researchers at the Center for Microbiome Innovation (CMI) at the University of California San Diego collaborated with L’Oréal Research and Innovation to analyze data collected during 13 studies from 650 female participants between the ages of 18 and 70 years.


“Previous studies have shown that the types of microbes on our skin change in a fairly predictable way with age,” said lead researcher Si Jin Song. “Our skin also changes physiologically with age. But there is a difference in what this looks like in individuals.”

He continued: “Using advanced statistical methods, we were able to separate the microbes associated with signs of skin aging from those associated with age simply as a chronological number.”


The analysis revealed two main results. First, the team found a positive association between the skin microbiome and crow’s feet, a sign of aging. Secondly, they found a negative relationship between the range of bacteria on the skin and the loss of moisture in the skin.

Although the team couldn’t say with certainty that one is caused by the other, they are excited about what it means for the next steps in anti-aging research.

Future Research

Co-author Qian Cheng, head of North American Advanced Research at L’Oréal, said: “This research is pioneering in identifying new microbial biomarkers associated with visible signs of aging such as crow’s feet. It represents an important step towards developing technologies for healthier, more youthful skin.”

Co-author Rob Knight added: “By confirming the relationship between the microbiome and skin health, we have laid the foundation for further studies that discover specific microbiome biomarkers related to skin aging, and one day, we will demonstrate how to modify them to create new, targeted recommendations for skin health.”

Source: New York Post

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