Machine learning patch design can help "treatment" hereditary baldness

Chinese researchers have created a tool that can help ‘cure’ hair loss using microneedle patches combined with artificial intelligence.

Many people suffer from androgenetic alopecia or androgenetic alopecia, a common hair loss condition in both men and women characterized by hair loss in well-defined areas starting from the front of the hair above the temples.

Doctors say the new technology could help restore lost hair because the patch neutralizes highly reactive chemicals that thin and eventually disappear, according to Nano Letters magazine.

The patch helped regenerate the hair of mice within 13 days of its use. The mice used to test the new patch restored thicker strands of hair more effectively than other mice treated with testosterone or the chemical minoxidil, which is used in anti-baldness products.

The hair follicles of people with male or female pattern baldness (or androgenetic alopecia) can be damaged by androgens, infections, or too many reactive oxygen species such as oxygen free radicals. And when oxygen free radical levels are too high, they can inhibit the body’s antioxidant enzymes that normally keep them in check.

One such enzyme is called superoxide dismutase, and researchers have recently created nanoenzymes for it called nanozymes.

The research team wanted to find out if machine learning, a form of artificial intelligence, could help develop better enzyme nanoparticles to treat hair loss.

They tested machine learning models with 91 groups. Experts expected manganese phosphorus trisulfide (MnPS3) to be the most powerful tool for the success of the process.

While tests were primarily done on mice, initial tests on human skin showed that it significantly reduced free radicals without causing any harm.

Lina Wang, study author from Qingdao University of Science and Technology, said: “Hair loss is not desirable for many men and women, as it is often closely related to their self-image. We used artificial intelligence (AI) to predict compounds that can neutralize it.” forms of oxygen that cause baldness of the scalp.

Source: Sun