Preeclampsia in pregnancy contributes to the development of encephalitis

The Mayo Hospital Information Office reported that acellular vesicles with particles of beta-amyloid protein associated with the development of Alzheimer’s disease were found in the blood of pregnant women with preeclampsia.

And doctors at Mayo Hospital note that preeclampsia, also called “preeclampsia,” is a severe increase in blood pressure in the last stages of pregnancy, increasing the risk of encephalitis and bleeding in its tissues.

Preeclampsia is a common disease in the developmental stage of the fetus, when a pregnant woman becomes infected with it, the pressure inside the vessels increases, her blood cells begin to die collectively, and the work of the liver and kidneys is seriously weakened. . This usually happens in the last months of pregnancy. Currently, there are no reliable methods for the early diagnosis of this disease. Therefore, doctors often detect it late in development by high concentrations of proteins in biological samples and high blood pressure. The causes of this disease are not yet clear, but scientists suggest that it occurs due to disturbances in the formation of blood vessels in the placenta.

The researchers followed the case of 40 women, including seven women who had a severe form of the disease, and the rest had a mild form. The researchers selected a similar number of pregnant women who did not develop the disease and compared the health outcomes of the two groups.

Doctors have found that the blood of women who contract the disease contains cell-free vesicles containing beta-amyloid protein particles associated with the development of Alzheimer’s disease. It is part of the cellular APP receptor, molecules of which are rarely found outside the cytoplasm of neurons in the healthy human brain.

Accordingly, the presence of beta-amyloid in the blood of women indicates a mass death of brain cells and the appearance of foci of inflammation in the nervous tissue.

According to experts, the continuation of this study will help determine the mechanism of brain damage in preeclampsia and ways to prevent it.

Source: TASS